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Spaglumic acid

CAS No. 3106-85-2

Spaglumic acid ( NAAG,N-Acetylaspartylglutamic acid )

Catalog No. M22700 CAS No. 3106-85-2

Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Spaglumic acid
  • Note
    Research use only, not for human use.
  • Brief Description
    Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors.
  • Description
    Spaglumic acid is a neuropeptide found in millimolar concentrations in the brain.Spaglumic Acid is released upon depolarization by a Ca2+-dependent process and is an agonist at mGluR3 receptors and an antagonist at NMDA receptors. Spaglumic Acid is catabolized to N-acetylaspartate and glutamate primarily by glutamate carboxypeptidase II, which is expressed on the extracellular surface of astrocytes.
  • Synonyms
    NAAG,N-Acetylaspartylglutamic acid
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Endogenous Metabolite
  • Recptor
    Human Endogenous Metabolite
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    3106-85-2
  • Formula Weight
    304.26
  • Molecular Formula
    C11H16N2O8
  • Purity
    >98% (HPLC)
  • Solubility
    Water:29 mg/mL(95.31 mM)
  • SMILES
    CC(=O)N[C@@H](CC(O)=O)C(=O)N[C@@H](CCC(O)=O)C(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1.Coyle JT. The nagging question of the function of N-acetylaspartylglutamate. Neurobiol Dis. 1997;4(3-4):231-8.
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